Description

3-Pyridinecarbonyl Chloride, 2-Chloro-4,6-Dimethyl- (9Ci) is a high-purity, reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce a functionalized nicotinoyl moiety, enabling the construction of complex molecular architectures with precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in material science for creating specialized functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and other small molecule therapeutic research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for creating functional polymers, dyes, and photoactive materials with tailored properties.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Custom Synthesis: Employed in contract manufacturing and fine chemical production for bespoke molecule assembly.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 2-Chloro-4,6-Dimethyl- (9Ci)
CAS No.	114319-42-5
Molecular Formula	C8H7Cl2NO
Molecular Weight	204.05 g/mol
Synonyms	2-Chloro-4,6-dimethylnicotinoyl chloride; 2-Chloro-4,6-dimethylpyridine-3-carbonyl chloride; 2-Chloro-4,6-dimethyl-3-pyridinecarbonyl chloride; 3-Carbonyl chloride-2-chloro-4,6-dimethylpyridine; 2-Chloro-4,6-lutidine-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 2-Chloro-4,6-Dimethyl- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.