Description

N(2)-Phenyl-2'-Deoxyguanosine is a chemically modified nucleoside derivative where a phenyl group is attached to the N2 position of the guanine base. This modification is crucial for research into nucleic acid structure, function, and the development of novel therapeutic agents. It is primarily utilized by researchers and developers in the fields of pharmaceutical development, oligonucleotide synthesis, and biochemical research.

Application

• Biochemical Research: Used as a key intermediate or probe in studying DNA structure, damage, and repair mechanisms.
• Antiviral/Anticancer Drug Development: Serves as a building block for the synthesis of nucleoside analogs with potential therapeutic activity.
• Oligonucleotide Synthesis: Incorporated into synthetic DNA strands to study base-pairing properties and stability of modified duplexes.
• Proteomics & Genomics: Acts as a tool compound in high-throughput screening assays and target identification.
• Diagnostic Reagent Development: Utilized in the creation of labeled probes for detection and diagnostic applications.
• Academic Research: Fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Item	Details
Product Name	N(2)-Phenyl-2'-Deoxyguanosine
CAS No.	114300-71-9
Molecular Formula	C16H17N5O4
Molecular Weight	343.34 g/mol
Synonyms	N2-Phenyl-2'-deoxyguanosine; N2-Phenyl-2'-deoxyguanosine; 2'-Deoxy-N2-phenylguanosine; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(phenylamino)-1H-purin-6-one; Phenyl-deoxyguanosine; dG(Phe)
EINECS	Contact for details

Quality Control

Our N(2)-Phenyl-2'-Deoxyguanosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.