Description

Cyclohexanecarbonyl Chloride, 2-(Acetyloxy)-, trans- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group and an acetyl-protected hydroxyl moiety on a cyclohexane ring. This compound matters as a high-value building block for synthesizing complex molecules, particularly in the pharmaceutical sector where its defined stereochemistry is crucial. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for constructing chiral scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis.
• Polymer Modification: Functional monomer for introducing cyclohexyl and ester groups into specialty polymers.
• Fine Chemical Production: Intermediate in the multi-step synthesis of fragrances, flavors, and other high-value fine chemicals.
• Academic & Contract Research: Valuable reagent for methodological development and exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 2-(Acetyloxy)-, trans- (9Ci)
CAS No.	114250-36-1
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	trans-2-(Acetyloxy)cyclohexanecarbonyl chloride; (1R,2R)-2-(Acetyloxy)cyclohexanecarbonyl chloride; (1S,2S)-2-(Acetyloxy)cyclohexanecarbonyl chloride; 2-Acetoxycyclohexanecarbonyl chloride, trans-; trans-2-Acetoxycyclohexanecarboxylic acid chloride; Cyclohexanecarboxylic acid, 2-(acetyloxy)-, chloride, trans-; 2-Acetyloxycyclohexanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Chloride, 2-(Acetyloxy)-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Isolate from incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.