Description

Cyclohexanecarbonyl Chloride, 2-(Acetyloxy)-, cis- (9Ci) is a specialized, high-purity chemical intermediate characterized by its reactive acid chloride and acetyl-protected hydroxyl functionalities. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce the cis-2-acetoxycyclohexanecarbonyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) or metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the cyclohexane scaffold is required.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce functional side chains into polymers, enhancing properties like biodegradability or specific reactivity.
• Fine Chemical and Flavor/Fragrance Precursor: Utilized in the multi-step synthesis of complex esters and other compounds for high-value specialty chemicals.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic synthesis, including new coupling and acylation reactions.

Basic Information

Item	Details
Product Name	Cyclohexanecarbonyl Chloride, 2-(Acetyloxy)-, cis- (9Ci)
CAS No.	114250-35-0
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	cis-2-(Acetyloxy)cyclohexanecarbonyl chloride; (1R,2S)-rel-2-(Acetyloxy)cyclohexanecarbonyl chloride; 2-Acetoxycyclohexanecarbonyl chloride, cis-; Cyclohexanecarbonyl chloride, 2-(acetyloxy)-, (1R,2S)-rel-; 2-Acetyloxycyclohexanecarbonyl Chloride; cis-2-Acetoxy-1-cyclohexanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarbonyl Chloride, 2-(Acetyloxy)-, cis- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and reliability for critical synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.