Description

Cholest-8(14)-Ene-3,26-Diol-15-One CAS NO 114182-43-3 is a high-purity, functionalized steroid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate for the development of novel bioactive molecules, particularly in the exploration of sterol-based therapeutics and signaling modulators. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new drug candidates, metabolic pathway studies, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drug candidates targeting metabolic and hormonal pathways.
• Biochemical Research: Used as a reference standard or probe in studies of sterol biosynthesis, enzyme inhibition, and receptor binding assays.
• Organic Synthesis: Serves as a versatile chiral precursor for the preparation of complex natural products and specialized fine chemicals.
• Academic Research: Employed in universities and R&D labs for methodological development in synthetic organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	Cholest-8(14)-Ene-3,26-Diol-15-One
CAS No.	114182-43-3
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	15-Oxo-27-norcholest-8(14)-ene-3,26-diol; 3,26-Dihydroxycholest-8(14)-en-15-one; 27-Norcholest-8(14)-ene-3,26-diol-15-one; 15-Keto-27-norcholest-8(14)-ene-3,26-diol; (3β,25R)-3,26-Dihydroxycholest-8(14)-en-15-one
EINECS	Contact for details

Quality Control

Our Cholest-8(14)-Ene-3,26-Diol-15-One is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with client requirements for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.