Description

2,6-Pyridinedicarbonyl Difluoride (9Ci) is a versatile and highly reactive fluorinated pyridine derivative used as a key building block in advanced organic synthesis. Its value lies in its ability to act as a bifunctional acylating agent, facilitating the efficient construction of complex heterocyclic and pharmaceutical intermediates. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those containing pyridine or amide functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands for metal catalysis and organocatalysts.
• Polymer and Material Science: Employed in the creation of functional polymers, dendrimers, and advanced materials with tailored properties.
• Chemical Biology Probes: Useful for modifying biomolecules or creating activity-based probes for studying enzymatic processes.
• Cross-coupling Reactions: Acts as an electrophilic partner in various cross-coupling methodologies to introduce the dicarbonyl difluoride moiety.

Basic Information

Item	Details
Product Name	2,6-Pyridinedicarbonyl Difluoride (9Ci)
CAS No.	114085-28-8
Molecular Formula	C7H3F2NO2
Molecular Weight	171.10 g/mol
Synonyms	Pyridine-2,6-dicarbonyl difluoride; 2,6-Difluorocarbonylpyridine; 2,6-Bis(fluorocarbonyl)pyridine; 2,6-Pyridinedicarboxylic acid difluoride; Difluoride of 2,6-pyridinedicarboxylic acid; Isophthaloyl difluoride, pyridine analog
EINECS	Contact for details

Quality Control

Our 2,6-Pyridinedicarbonyl Difluoride is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity and spectroscopic identification (IR, NMR). Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.