Description

2,2-Dimethylbut-3-Ynoyl Chloride is a specialized acid chloride derivative characterized by its terminal alkyne and neopentyl-like structure, making it a valuable building block in advanced organic synthesis. This compound matters for its ability to efficiently introduce the sterically hindered 2,2-dimethylbut-3-ynoyl moiety into target molecules, enabling the creation of complex architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring sterically hindered acetylene functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the specific molecular framework contributes to biological activity.
• Material Science Research: Serves as a monomer or precursor for polymers and advanced materials with tailored properties.
• Organic Synthesis Reagent: Employed in amidation and esterification reactions to install the 2,2-dimethylbut-3-ynoyl group onto amines, alcohols, or other nucleophiles.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules via click chemistry reactions facilitated by the alkyne group.
• Fine Chemical Production: Integral in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	2,2-Dimethylbut-3-Ynoyl Chloride
CAS No.	114081-07-1
Molecular Formula	C6H7ClO
Molecular Weight	130.57 g/mol
Synonyms	2,2-Dimethylbut-3-ynoic acid chloride; 3,3-Dimethylbut-2-ynoyl chloride; 2,2-Dimethyl-3-butynoyl chloride; TMS-Propargyl acid chloride (derivative); 3-Butynoic acid, 2,2-dimethyl-, chloride; 2,2-Dimethylbut-3-ynoyl chloride; 2,2-Dimethyl-3-butynoic acid chloride
EINECS	Contact for details

Quality Control

Our 2,2-Dimethylbut-3-Ynoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, it should be stored separately from bases, oxidizing agents, and moisture-sensitive materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.