Description

Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride, 5,7-Dimethyl- (9Ci) is a high-value, reactive chemical intermediate primarily used in advanced organic synthesis. This compound matters because its unique pyrazolopyrimidine scaffold and acid chloride functionality make it a critical building block for constructing complex heterocyclic molecules with potential biological activity. It is essential for research and development chemists in the pharmaceutical and agrochemical industries who require reliable, high-purity intermediates for creating novel active ingredients. The compound, identified by CAS number 114040-07-2, is a cornerstone for innovation in medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazolopyrimidine core for bioactivity.
• Chemical Research & Development: A versatile building block for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Potential use in the synthesis of organic electronic materials and advanced polymers due to its conjugated ring system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized fine chemicals and APIs (Active Pharmaceutical Ingredients).

Basic Information

Item	Details
Product Name	Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride, 5,7-Dimethyl- (9Ci)
CAS No.	114040-07-2
Molecular Formula	C9H8ClN3O
Molecular Weight	209.63 g/mol
Synonyms	5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride; 5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chloride; 114040-07-2; Pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride, 5,7-dimethyl-; 5,7-Dimethyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride; 5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carbonyl chloride (9CI)
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride, 5,7-Dimethyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results. We are committed to meeting the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, this material must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container tightly sealed in a dry environment to prevent hydrolysis of the acid chloride group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.