Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3-Ethenyl-, [1S-(Endo,Endo)]- (9Ci) is a highly specialized, chiral bicyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique, rigid molecular framework and reactive carbonyl chloride group, enabling the precise construction of complex, stereodefined molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials where specific three-dimensional shape is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially those targeting the central nervous system or requiring specific receptor binding.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with enhanced stereospecificity and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Employed in the synthesis of specialty polymers with unique thermal or mechanical properties derived from the norbornene structure.
• Material Science Research: Acts as a building block for advanced organic materials, such as liquid crystals or molecularly imprinted polymers.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and total synthesis projects.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3-Ethenyl-, [1S-(Endo,Endo)]- (9Ci)
CAS No.	113773-86-7
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	(1S,2S,4R)-3-Ethenylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; (1S,2S,4R)-3-Vinylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 3-Vinyl-5-norbornene-2-carbonyl chloride, (1S-endo,2S-endo)-; endo,endo-3-Vinylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; Chiral Norbornene Acid Chloride; 3-Ethenylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, (1S,2S,4R)-
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3-Ethenyl-, [1S-(Endo,Endo)]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and enantiomeric excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.