Description

Ethanol, 2-Azido-, 4-Methylbenzenesulfonate (Ester) is a specialized organic intermediate featuring a reactive azido functional group, making it a valuable synthon for click chemistry applications, particularly in the synthesis of triazole derivatives. This compound is crucial for researchers and manufacturers requiring precise, high-purity building blocks for pharmaceutical development and advanced material science. It is primarily utilized by R&D chemists in the pharmaceutical, agrochemical, and bioconjugation sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Huisgen 1,3-dipolar cycloaddition (click chemistry).
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its azide group for efficient heterocycle formation.
• Bioconjugation & Probe Development: Enables the labeling and modification of biomolecules (proteins, peptides, nucleic acids) for diagnostic and research applications.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent in the development of advanced polymers with tailored properties.
• Chemical Biology Research: A versatile tool for activity-based protein profiling (ABPP) and the study of biological pathways.
• Ligand & Catalyst Development: Used in the preparation of novel ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Ethanol, 2-Azido-, 4-Methylbenzenesulfonate (Ester)
CAS No.	113738-22-0
Molecular Formula	C9H11N3O3S
Molecular Weight	241.27 g/mol
Synonyms	2-Azidoethyl p-Toluenesulfonate; p-Toluenesulfonic Acid 2-Azidoethyl Ester; 2-Azidoethanol Tosylate; Tosyl Azide Ethanol Ester; 2-Azidoethyl Tosylate; 4-Methylbenzenesulfonic Acid 2-Azidoethyl Ester; (2-Azidoethoxy)(4-methylphenyl)sulfone (incorrect but common search term); Azidoethyl Tosylate
EINECS	Contact for details

Quality Control

Our Ethanol, 2-Azido-, 4-Methylbenzenesulfonate (Ester) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.