Description

o-Demethylpaulomycin B is a chemically modified derivative of the paulomycin family of antibiotics, representing a key intermediate in pharmaceutical research and development. This compound matters for its role in the study of structure-activity relationships and as a precursor in the synthesis of novel antimicrobial agents. It is primarily needed by research institutions and pharmaceutical companies engaged in antibiotic discovery, medicinal chemistry, and the development of new therapeutic compounds targeting resistant bacterial strains.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis and structural optimization of new paulomycin-derived antibiotics.
• Medicinal Chemistry Studies: Used to investigate the impact of specific molecular modifications on biological activity and pharmacokinetic properties.
• Antimicrobial Agent Development: A key precursor in R&D programs focused on creating novel agents against drug-resistant bacteria.
• Biochemical Research: Employed in studies to understand the mechanism of action of ansamycin-class antibiotics.
• Reference Standard: Utilized as an analytical standard in quality control and method development for related pharmaceutical compounds.

Basic Information

Product Name	o-Demethylpaulomycin B
CAS No.	113592-08-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Paulomycin B, o-Demethyl derivative; Demethylpaulomycin B; 2'-Demethylpaulomycin B; Antibiotic U-67957; Ansamycin antibiotic derivative; Paulomycin derivative; 113592-08-8; U-67957
EINECS	Contact for details

Quality Control

Our o-Demethylpaulomycin B is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.