Description

(S)-Benzyl 2-Azido-2-Phenylethanoate CAS NO 113543-52-5 is a high-purity chiral building block and azide derivative, essential for advanced organic synthesis and pharmaceutical research. Its primary value lies in its role as a key intermediate for the synthesis of complex molecules, particularly through click chemistry and peptide coupling reactions. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of β-amino acids, unnatural amino acids, and peptidomimetics with potential therapeutic applications.
• Click Chemistry Reagent: The azido group enables efficient, high-yielding Huisgen 1,3-dipolar cycloaddition reactions with alkynes to form triazoles, a cornerstone of bioconjugation and material science.
• Peptide Synthesis: Used in the preparation of azido-functionalized amino acid derivatives for solid-phase peptide synthesis (SPPS) and the construction of modified peptides.
• Agrochemical Research: Serves as a building block for creating novel chiral compounds with potential herbicidal or insecticidal activity.
• Material Science: Employed in the development of functional polymers, dendrimers, and surface coatings via polymer-analogous reactions.
• Chemical Biology Probes: Facilitates the labeling and study of biomolecules through bioorthogonal chemistry techniques.

Basic Information

Item	Details
Product Name	(S)-Benzyl 2-Azido-2-Phenylethanoate
CAS No.	113543-52-5
Molecular Formula	C15H13N3O2
Molecular Weight	267.28 g/mol
Synonyms	(S)-Benzyl Azido(phenyl)acetate; (S)-Benzyl 2-Azido-2-phenylacetate; (S)-α-Azidobenzeneacetic Acid Benzyl Ester; (S)-Benzyl α-Azidophenylacetate; L-Benzyl Azido(phenyl)acetate; (2S)-2-Azido-2-phenylacetic Acid Benzyl Ester; Benzyl (S)-2-azido-2-phenylacetate
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-Azido-2-Phenylethanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure consistent high quality and enantiomeric excess suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the presence of the azide functional group, avoid exposure to heat, strong reducing agents, and heavy metals. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.