Description

Thiocyanic Acid, 2-Fluorocyclohexyl Ester, cis- (9Ci) is a specialized organofluorine building block featuring a thiocyanate functional group on a fluorinated cyclohexane scaffold. This compound matters for its unique reactivity profile, enabling the introduction of both fluorine and thiocyanate moieties in advanced synthetic pathways. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for introducing sulfur-containing functional groups.
• Agrochemical Synthesis: Used in the preparation of advanced pesticides and herbicides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and coordination chemistry.
• Fluorine Chemistry Research: A valuable substrate for exploring new fluorination reactions and the stereoelectronic effects of the cis-2-fluoro configuration.

Basic Information

Product Name	Thiocyanic Acid, 2-Fluorocyclohexyl Ester, cis- (9Ci)
CAS No.	113487-46-0
Molecular Formula	C7H10FNS
Molecular Weight	159.22 g/mol
Synonyms	cis-2-Fluorocyclohexyl thiocyanate; (1R,2S)-2-Fluorocyclohexyl thiocyanate (and enantiomer); 2-Fluorocyclohexyl thiocyanate, cis-; NSC 405122; Thiocyanic acid, 2-fluorocyclohexyl ester, cis-; cis-2-Fluorocyclohexyl isothiocyanate (common misnomer); Fluorocyclohexyl thiocyanate
EINECS	Contact for details

Quality Control

Every batch of Thiocyanic Acid, 2-Fluorocyclohexyl Ester, cis- (9Ci) is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data including HPLC purity, NMR confirmation, and GC analysis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.