Description

3-Thiophenecarbonyl Chloride, 5-Chloro- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling precise molecular construction for high-value fine chemicals and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce thiophene-based motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with thiophene cores for enhanced efficacy and environmental profile.
• Material Science & Organic Electronics: Building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and photovoltaic materials.
• Ligand & Catalyst Development: Facilitates the creation of novel ligands for transition metal catalysis and organocatalysts.
• Custom Synthesis & Contract Research: Employed by CROs and CDMOs for client-specific projects requiring tailored thiophene derivatives.
• Chemical Research: Fundamental reagent in academic and industrial R&D for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	3-Thiophenecarbonyl Chloride, 5-Chloro- (9Ci)
CAS No.	113471-08-2
Molecular Formula	C5H2Cl2OS
Molecular Weight	181.04 g/mol
Synonyms	5-Chloro-3-thiophenecarbonyl chloride; 5-Chlorothiophene-3-carbonyl chloride; 5-Chloro-3-thenoyl chloride; 3-Thenoyl chloride, 5-chloro-; 5-Chloro-3-thienoyl chloride; 5-Chloro-3-thiophenecarboxylic acid chloride; 5-Chloro-3-thiophenoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonyl Chloride, 5-Chloro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with lot-specific data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and reactive nature. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.