Description

Grincamycin is a potent anthracycline-class antibiotic compound, identified by CAS No. 113395-84-9. This molecule is valued for its significant biological activity, particularly as a DNA intercalator and topoisomerase inhibitor, making it a crucial entity in biochemical and pharmacological research. It is primarily utilized by research institutions and pharmaceutical developers focused on oncology, antimicrobial discovery, and molecular biology.

Application

• Anticancer Research: Serves as a key reference standard and active compound in studies targeting DNA damage and apoptosis mechanisms in various cancer cell lines.
• Antimicrobial Agent Development: Investigated for its potent activity against Gram-positive bacteria and its potential in overcoming antibiotic resistance.
• Biochemical Tool Compound: Used in enzymatic assays to study the inhibition of topoisomerase II and other nucleic acid-interacting enzymes.
• Pharmaceutical Intermediate: Acts as a sophisticated building block or a lead compound in the synthesis and development of novel therapeutic agents.
• Mechanistic Studies: Employed in academic and industrial research to elucidate the structure-activity relationships (SAR) of anthracycline derivatives.

Basic Information

Item	Detail
Product Name	Grincamycin
CAS No.	113395-84-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Grincamycin; Antibiotic DC 92; DC 92; 7-O-Methylnogalarol; 10-Demethoxy-13-deoxo-13-oxodaunorubicin; (7S,9S)-9-Acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
EINECS	Contact for details

Quality Control

Our Grincamycin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is characterized using advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided. We support research standards that may align with pharmacopeial guidelines for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Red to orange powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.