Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3,5-Dimethyl-, (2-Endo,3-Exo)- (9Ci) is a highly functionalized, stereochemically defined norbornene derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the precise spatial arrangement of its functional groups, enabling the construction of complex molecular architectures with high stereochemical fidelity. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating specialized polymers and ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for creating novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Advanced Material Precursor: Used in the development of specialty polymers, including polyolefins with unique tacticity and performance materials via ring-opening metathesis polymerization (ROMP).
• Catalyst & Ligand Development: Serves as a precursor for synthesizing chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: A valuable tool for methodological development in organic synthesis, particularly in studies of stereoselective reactions and cycloadditions.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3,5-Dimethyl-, (2-Endo,3-Exo)- (9Ci)
CAS No.	113351-13-6
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	(2-Endo,3-Exo)-3,5-Dimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 3,5-Dimethyl-2-norbornenecarbonyl chloride (endo,exo); (1S,2R,4R)-4,6-Dimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; endo,exo-3,5-Dimethyl-5-norbornene-2-carbonyl chloride; Norbornene carbonyl chloride derivative; Bicyclo[2.2.1]hept-2-ene-2-carbonyl chloride, 3,5-dimethyl-, (1S,2R,4R)-rel-
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3,5-Dimethyl-, (2-Endo,3-Exo)- (9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, this material should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and maintain purity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.