Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3,6-Dimethyl-, (2-Endo,3-Exo)- (9Ci) is a highly reactive and stereochemically defined bicyclic acid chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in the precise introduction of the dimethyl-substituted norbornene scaffold, which is instrumental for constructing complex molecular architectures with defined three-dimensional geometry. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for creating novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profile.
• Advanced Material Monomer: Used in polymerization reactions to produce specialty polymers with unique thermal, mechanical, or optical properties for high-performance applications.
• Catalyst & Ligand Development: Precursor for synthesizing novel chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & Process R&D: Enables exploration of new synthetic methodologies and reaction pathways in organic chemistry research.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance and flavor molecules.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3,6-Dimethyl-, (2-Endo,3-Exo)- (9Ci)
CAS No.	113283-37-7
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	(2-endo,3-exo)-3,6-Dimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; 3,6-Dimethyl-2-norbornenecarbonyl chloride (endo,exo); (1R,2S,3R,4S)-3,6-Dimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; endo,exo-3,6-Dimethyl-5-norbornene-2-carbonyl chloride; Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, 3,6-dimethyl-, (1R,2S,3R,4S)-; (1S,2R,3S,4R)-3,6-Dimethylbicyclo[2.2.1]hept-5-ene-2-carbonyl chloride (enantiomer)
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, 3,6-Dimethyl-, (2-Endo,3-Exo)- (9Ci) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, critical for your sensitive downstream reactions. Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), enantiomeric/excess, and impurity profiles are available upon request and are prepared to meet the stringent requirements of cGMP and ISO 9001 standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Isomeric Purity (endo,exo)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.