Description

3'-o-Acetyl-2'-Deoxy-5-Methoxymethyluridine is a chemically modified nucleoside derivative, serving as a critical building block in advanced oligonucleotide synthesis. This high-purity intermediate is essential for researchers and manufacturers developing novel therapeutic agents and diagnostic tools. It is primarily utilized in the pharmaceutical and biotechnology sectors for the production of modified antisense oligonucleotides and other nucleic acid-based therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of modified nucleoside analogs for antiviral and anticancer drug development.
• Antisense Oligonucleotide Synthesis: Building block for introducing specific modifications into oligonucleotide chains to enhance stability and binding affinity.
• Prodrug Development: Used in the design of prodrugs to improve the bioavailability and targeted delivery of nucleoside-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Valuable tool in studying enzyme mechanisms, nucleic acid interactions, and metabolic pathways in academic and industrial R&D.
• Diagnostic Probe Synthesis: Component in the manufacture of labeled probes for genetic testing and molecular diagnostics.

Basic Information

Product Name	3'-o-Acetyl-2'-Deoxy-5-Methoxymethyluridine
CAS No.	113203-27-3
Molecular Formula	C13H18N2O7
Molecular Weight	314.29 g/mol
Synonyms	5'-O-Acetyl-2'-deoxy-5-methoxymethyluridine; 2'-Deoxy-5-methoxymethyluridine 3'-acetate; 3'-O-Acetyl-5-methoxymethyl-2'-deoxyuridine; 5-Methoxymethyl-2'-deoxyuridine 3'-acetate; dU(MOM) 3'-O-Acetate; 113203-27-3; Modified Nucleoside; Nucleoside Intermediate
EINECS	Contact for details

Quality Control

Our 3'-o-Acetyl-2'-Deoxy-5-Methoxymethyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.