Description

Cyclopropanecarbonyl Chloride, 1,2,2-Trichloro- (9Ci) is a specialized halogenated cyclopropane derivative that serves as a high-value synthetic intermediate. Its unique sterically hindered structure and reactive acid chloride functional group make it a critical building block for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to introduce the cyclopropane moiety into target molecules, a key strategy for modulating bioactivity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring can enhance stability and biological activity.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the synthesis of activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 1,2,2-Trichloro- (9Ci)
CAS No.	112906-13-5
Molecular Formula	C4H2Cl4O
Molecular Weight	209.87 g/mol
Synonyms	1,2,2-Trichlorocyclopropanecarbonyl chloride; Trichlorocyclopropanecarbonyl chloride; (1,2,2-Trichlorocyclopropyl)carbonyl chloride; Cyclopropanecarbonyl chloride, 1,2,2-trichloro-; 1,2,2-Trichloro-1-cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarbonyl Chloride, 1,2,2-Trichloro- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles as determined by techniques including GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.