Description

2,4-Difluoro-3-Methylbenzoyl Chloride is a high-value, multi-functional aromatic acid chloride intermediate. This compound is critical for introducing the 2,4-difluoro-3-methylbenzoyl moiety into target molecules, enabling precise structural modifications. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro and methyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic compounds used in electronic display technologies.
• Polymer Modification: Employed to introduce specific aromatic fluorinated side chains into polymers to alter thermal, chemical, or surface properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.
• Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction methodologies involving acyl chlorides.

Basic Information

Product Name	2,4-Difluoro-3-Methylbenzoyl Chloride
CAS No.	112857-70-2
Molecular Formula	C8H5ClF2O
Molecular Weight	190.57 g/mol
Synonyms	3-Methyl-2,4-difluorobenzoyl chloride; 2,4-Difluoro-3-methylbenzoic acid chloride; 2,4-Difluoro-m-toluoyl chloride; 3-Methyl-2,4-difluorobenzoic acid chloride; Benzoyl chloride, 2,4-difluoro-3-methyl-; α,2,4-Trifluoro-3-methylbenzoyl chloride (obsolete); 2,4-Difluoro-3-methyl-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methylbenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.