Description

Calcipotriene is a synthetic vitamin D3 analog that acts as a potent regulator of skin cell production and differentiation. This compound is of critical importance in the pharmaceutical industry for the development of topical treatments for chronic skin conditions. It is primarily required by pharmaceutical manufacturers and research institutions focused on dermatological therapeutics, particularly for psoriasis management.

Application

• Active Pharmaceutical Ingredient (API) in topical ointments, creams, and solutions for the treatment of plaque psoriasis.
• Key Intermediate in the synthesis of more complex vitamin D receptor modulators for research purposes.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research for studying calcium metabolism, cell proliferation, and immune modulation pathways.
• Formulation Development for novel drug delivery systems targeting dermatological applications.

Basic Information

Product Name	Calcipotriene
CAS No.	112828-00-9
Molecular Formula	C27H40O3
Molecular Weight	412.61 g/mol
Synonyms	Calcipotriol; MC 903; (5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol; Daivonex; Dovonex; Psorcutan
EINECS	Contact for details

Quality Control

Our Calcipotriene is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical development. A comprehensive Certificate of Analysis (COA) is supplied with each batch, detailing parameters such as assay, related substances, and residual solvents. Our quality commitment ensures consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.