Description

2,4,5-Trifluoro-3-Methoxybenzoyl Chloride is a highly reactive and versatile aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which enable precise modulation of electronic and steric properties in target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex intermediates for active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoyl moiety.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of fluorine-substituted aromatics.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Monomer or modifying agent for creating specialty polymers with enhanced chemical resistance or specific optical properties.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation, amide coupling, and esterification reactions to introduce the 2,4,5-trifluoro-3-methoxybenzoyl group.
• Material Science Research: Intermediate in the development of organic semiconductors and other advanced electronic materials.

Basic Information

Item	Detail
Product Name	2,4,5-Trifluoro-3-Methoxybenzoyl Chloride
CAS No.	112811-66-2
Molecular Formula	C8H4ClF3O2
Molecular Weight	232.56 g/mol
Synonyms	3-Methoxy-2,4,5-trifluorobenzoyl chloride; 2,4,5-Trifluoro-3-methoxybenzoic acid chloride; 2,4,5-Trifluoro-m-anisoyl chloride; Benzoyl chloride, 2,4,5-trifluoro-3-methoxy-; 2,4,5-Trifluoro-3-methoxybenzoyl chloride; 3-Methoxy-2,4,5-trifluorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Our production of 2,4,5-Trifluoro-3-Methoxybenzoyl Chloride adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.