Description

2-Oxabicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-3-Oxo-, (1S)- (9Ci) is a high-purity, chiral bicyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique, rigid molecular framework and high reactivity, enabling the efficient construction of complex, stereochemically defined target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic structure contributes to specific biological activity.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Asymmetric Catalysis Ligand Synthesis: Employed as a starting material for constructing sophisticated chiral ligands and organocatalysts.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and the exploration of new chemical spaces.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals for various technological applications.

Basic Information

Item	Details
Product Name	2-Oxabicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-3-Oxo-, (1S)- (9Ci)
CAS No.	112457-40-6
Molecular Formula	C9H11ClO3
Molecular Weight	202.63 g/mol
Synonyms	(1S)-7,7-Dimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride; (1S)-Camphor-10-sulfonyl chloride (related derivative); 1S-(-)-10-Camphorsulfonyl chloride analog; Bicyclo[2.2.1]heptane-1-carbonyl chloride, 2-oxa-7,7-dimethyl-3-oxo-, (1S)-; L-(-)-Camphor based acid chloride; (1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride (isomeric); Chiral camphor sulfonyl chloride derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-Oxabicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-3-Oxo-, (1S)- (9Ci) is produced and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, store in a cool (2-8°C recommended), dry, and well-ventilated place under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.