Description

Cyclohexanecarbonyl Chloride, 2-Methyl-5-(1-Methylethyl)-, [1R-(1Alpha,2Beta,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral intermediate essential for advanced organic synthesis. This compound matters because its specific stereochemistry and reactive acid chloride group make it a critical building block for creating complex molecules with precise three-dimensional structures. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of stereospecific drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring high isomeric purity.
• Academic & Industrial Research: A valuable reagent for methodological development in asymmetric synthesis and catalysis studies.
• Peptide & Polymer Chemistry: The acid chloride functionality allows for efficient acylation reactions in peptide coupling or polymer modification.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 2-Methyl-5-(1-Methylethyl)-, [1R-(1Alpha,2Beta,5Alpha)]- (9Ci)
CAS No.	112321-33-2
Molecular Formula	C11H19ClO
Molecular Weight	202.72 g/mol
Synonyms	(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanecarbonyl chloride; (-)-Menthyl chloroformate (specific isomer); (1R,2S,5R)-Menthyl chloroformate; L-Menthyl chloroformate; [1R-(1α,2β,5α)]-2-Methyl-5-(1-methylethyl)cyclohexanecarbonyl chloride; (1R,2S,5R)-1,2,5-Trimethyl-4-(chlorocarbonyl)cyclohexane; (-)-Menthyl carbonochloridate; 2-Isopropyl-5-methylcyclohexanecarbonyl chloride (stereospecific)
EINECS	Contact for details

Quality Control

Every batch of our Cyclohexanecarbonyl Chloride, 2-Methyl-5-(1-Methylethyl)-, [1R-(1Alpha,2Beta,5Alpha)]- (9Ci) undergoes rigorous analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing parameters such as assay, enantiomeric excess, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Isolate from incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.