Description

1,3-Benzodioxole-5-Carbonyl Chloride, 2-Oxo- (9Ci) is a highly reactive and versatile chemical building block, specifically an acid chloride derivative of a substituted benzodioxole. This compound is critical for introducing the 2-oxo-1,3-benzodioxole-5-carbonyl moiety into target molecules, enabling the synthesis of complex structures with high precision. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research for novel drug candidates.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, where the benzodioxole scaffold is a common bioactive motif.
• Organic Synthesis Building Block: Serves as a crucial reagent for amide bond formation and other acylations in complex multi-step organic syntheses within R&D laboratories.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands, or functional materials that require specific aromatic heterocyclic components.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and tags used in biochemical and pharmacological studies.

Basic Information

Product Name	1,3-Benzodioxole-5-Carbonyl Chloride, 2-Oxo- (9Ci)
CAS No.	112057-04-2
Molecular Formula	C8H3ClO4
Molecular Weight	198.56 g/mol
Synonyms	2-Oxo-2H-1,3-benzodioxole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1,3-benzodioxol-2-one; 2-Oxo-1,3-benzodioxole-5-carboxylic acid chloride; 1,3-Benzodioxol-2-one-5-carbonyl chloride; 5-Carboxyphthalide acid chloride; 2-Oxo-1,3-benzodioxol-5-yl carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1,3-Benzodioxole-5-Carbonyl Chloride, 2-Oxo- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.