Description

N(6)-Octylamine Adenosine is a chemically modified nucleoside derivative where an octylamine group is attached to the N6 position of the adenine base. This modification is critical for enhancing the lipophilicity and membrane permeability of the adenosine molecule, making it a valuable intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for creating novel therapeutic agents, particularly in areas like oncology, cardiology, and neurology. The compound's unique structure allows for targeted drug delivery and improved pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel adenosine receptor agonists and antagonists with enhanced bioavailability.
• Bioconjugation & Probe Development: Used to create fluorescent or affinity-labeled probes for studying adenosine signaling pathways and receptor localization.
• Lipid-Nucleotide Conjugate Research: Serves as a precursor for developing lipid-conjugated nucleotides to improve cellular uptake in drug and gene delivery systems.
• Enzyme Inhibition Studies: Employed in biochemical assays to investigate the activity of enzymes like adenosine deaminase and kinases.
• Apoptosis & Cell Signaling Research: Utilized in experimental models to study the role of modified adenosine analogs in programmed cell death and intracellular communication.
• Preclinical Drug Candidate: Acts as a lead compound for developing potential therapeutics targeting cardiovascular diseases, inflammatory conditions, and certain cancers.

Basic Information

Product Name	N(6)-Octylamine Adenosine
CAS No.	111863-56-0
Molecular Formula	C₁₈H₃₀N₆O₄
Molecular Weight	394.47 g/mol
Synonyms	6-(Octylamino)purine riboside; N6-Octyladenosine; Adenosine, N-(octyl)-; 6-Octylaminoadenosine; N6-(n-Octyl)adenosine; Octylamino-adenosine; 6-N-Octylaminoadenosine; N6-Octyl-adenosine
EINECS	Contact for details

Quality Control

Our N(6)-Octylamine Adenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications can be aligned with cGMP requirements for advanced preclinical and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.