Description

3-Thiophenecarbonyl Chloride, 5-(Ethoxymethyl)- (9Ci) is a specialized organosulfur building block featuring a reactive acid chloride group and an ethoxymethyl substituent on the thiophene ring. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed to create novel thiophene-containing ligands for metal catalysis and coordination chemistry applications.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-Thiophenecarbonyl Chloride, 5-(Ethoxymethyl)- (9Ci)
CAS No.	111859-83-7
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	5-(Ethoxymethyl)thiophene-3-carbonyl chloride; 5-(Ethoxymethyl)-3-thiophenecarbonyl chloride; 3-Carbonyl chloride-5-ethoxymethylthiophene; 5-Ethoxymethylthiophene-3-carboxylic acid chloride; Thiophene-3-carbonyl chloride, 5-(ethoxymethyl)-; 111859-83-7; 5-(Ethoxymethyl)thiophene-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonyl Chloride, 5-(Ethoxymethyl)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.