Description

2-Bromo-5-Fluorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce both bromine and fluorine substituents, along with a reactive carbonyl chloride group, into target molecules in a single step. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise functionalization for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the bromo-fluoro-benzoyl moiety imparts specific biological activity and stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for advanced electronic materials, where halogenated aromatic structures are crucial for tuning electronic properties.
• Polymer Modification: Employed to introduce functional side chains into polymers, enhancing material characteristics like thermal stability or solubility.
• Peptide & Protein Research: Can be used as a coupling agent or for modifying amino acid side chains in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Item	Details
Product Name	2-Bromo-5-Fluorobenzoyl Chloride
CAS No.	111771-13-2
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	5-Fluoro-2-bromobenzoyl chloride; 2-Bromo-5-fluorobenzoic acid chloride; Benzoic acid, 2-bromo-5-fluoro-, chloride; 2-Bromo-5-fluorobenzoyl chloride; (2-Bromo-5-fluorophenyl)(chloro)methanone
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluorobenzoyl Chloride is produced and tested under a stringent quality management system. We guarantee high purity and consistent performance through rigorous analytical controls including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.