Description

2-Fluoro-6-Iodobenzoyl Chloride is a high-purity, functionalized benzoyl chloride derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of halogen atoms, which enable selective cross-coupling reactions and further derivatization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine and iodine substituents influence bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of monomers or functional units for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules due to the reactivity of the acid chloride group and the potential for radioiodination.
• Custom Fine Chemical Production: A versatile reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Product Name	2-Fluoro-6-Iodobenzoyl Chloride
CAS No.	111771-12-1
Molecular Formula	C7H3ClFIO
Molecular Weight	299.45 g/mol
Synonyms	2-Fluoro-6-iodobenzoic acid chloride; 6-Iodo-2-fluorobenzoyl chloride; Benzoic acid, 2-fluoro-6-iodo-, chloride; o-Fluoro-o'-iodobenzoyl chloride; 2-Fluoro-6-iodobenzoylchloride; 111771-12-1; 2-Fluoro-6-iodo-benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Iodobenzoyl Chloride is produced and tested to meet the stringent requirements of research and industrial synthesis. Each batch undergoes rigorous analytical control, including HPLC for purity verification and NMR for structural confirmation, to ensure consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.