Description

2-Chloro-9-(2-Chloro-2-Deoxy-β-D-Arabinofuranosyl)Purin-6-Amine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly within the field of nucleoside chemistry. Pharmaceutical companies, biotechnology research firms, and advanced academic laboratories engaged in drug discovery require this precise chemical for developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of experimental compounds targeting viral polymerases and reverse transcriptases.
• Oncology Drug Discovery: Serves as a precursor in the creation of potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in studies of enzyme kinetics, inhibition mechanisms, and structure-activity relationships (SAR) of nucleoside analogs.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	2-Chloro-9-(2-Chloro-2-Deoxy-β-D-Arabinofuranosyl)Purin-6-Amine
CAS No.	111615-20-4
Molecular Formula	C10H11Cl2N5O3
Molecular Weight	304.13 g/mol
Synonyms	2-Chloro-2'-deoxy-β-D-arabinofuranosyl-6-aminopurine; 2-Chloro-ara-2'-deoxyadenosine; 2-Chloro-2'-deoxy-β-D-arabinoadenine; 2-Cl-2'-deoxy-β-D-ara-A; 2-Chloro-9-(2-chloro-2-deoxy-β-D-arabinofuranosyl)adenine; 2-Chloro-2'-deoxy-β-D-arabinofuranosyladenine; 2-Chloro-2'-deoxy-arabinoadenosine
EINECS	Contact for details

Quality Control

Our 2-Chloro-9-(2-Chloro-2-Deoxy-β-D-Arabinofuranosyl)Purin-6-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.