Description

5-Amino-1-Ribofuranosyl-1,2,4-Triazole-3-Carboxamidine is a specialized nucleoside analogue with a unique triazole-carboxamidine structure, offering significant value as a key building block in advanced pharmaceutical research and development. This compound is critical for scientists developing novel antiviral and anticancer therapeutics, particularly those targeting nucleoside metabolic pathways. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of next-generation bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine and nucleoside metabolism.
• Proteomics & Molecular Biology: Employed in the development of chemical probes for studying nucleic acid-protein interactions and cellular signaling pathways.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of therapeutic agents.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Amino-1-Ribofuranosyl-1,2,4-Triazole-3-Carboxamidine
CAS No.	111379-66-9
Molecular Formula	C9H14N6O4
Molecular Weight	270.25 g/mol
Synonyms	5-Amino-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine; 1-(β-D-Ribofuranosyl)-5-amino-1,2,4-triazole-3-carboxamidine; 5-Amino-1-(β-D-ribofuranosyl)-1,2,4-triazole-3-carboxamidine; 5-Amino-1-ribofuranosyl-1,2,4-triazole-3-carboxamidine; 5-Amino-1-β-D-ribofuranosyl-v-triazole-3-carboxamidine; 5-Amino-1-(β-D-ribofuranosyl)-v-triazole-3-carboxamidine; 5-Amino-1-ribofuranosyl-v-triazole-3-carboxamidine
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Ribofuranosyl-1,2,4-Triazole-3-Carboxamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.