Description

(2E)-3-(5-Methyl-2-Furyl)Acryloyl Chloride CAS NO 111252-41-6 is a specialized, high-purity organic acid chloride derivative of a furan-acrylic acid. This compound matters as a critical building block in advanced organic synthesis, enabling the efficient introduction of the (5-methyl-2-furyl)acryloyl moiety into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting specific biological pathways.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the furan ring contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or electronic properties.
• Ligand and Catalyst Development: Employed in the creation of complex organic ligands for metal catalysis and asymmetric synthesis.
• Peptide Mimetics and Bioconjugation: The reactive acid chloride group facilitates coupling reactions for creating peptide analogs or labeling biomolecules.
• Fine Chemical Production: Integral in multi-step syntheses of complex fragrance, flavor, and dye intermediates.

Basic Information

Product Name	(2E)-3-(5-Methyl-2-Furyl)Acryloyl Chloride
CAS No.	111252-41-6
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	(E)-3-(5-Methylfuran-2-yl)acryloyl chloride; 3-(5-Methyl-2-furyl)-2-propenoyl chloride; trans-3-(5-Methyl-2-furyl)acryloyl chloride; 5-Methyl-2-furanacrylic acid chloride; 2-Propenoyl chloride, 3-(5-methyl-2-furanyl)-, (2E)-; (E)-3-(5-Methyl-2-furyl)propenoyl chloride
EINECS	Contact for details

Quality Control

Our (2E)-3-(5-Methyl-2-Furyl)Acryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Clear, light yellow to amber liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.