Description

2-Cyclohexene-1-Carbonyl Chloride, 4-Methyl-, trans- (9Ci) is a versatile and highly reactive acid chloride derivative of a substituted cyclohexene carboxylic acid. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of the 4-methyl-trans-2-cyclohexenoyl moiety into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex cyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific stereochemistry.
• Peptide Mimetics & Conjugation: Facilitates the acylation of amines in peptides or other biomolecules to create peptide mimetics or antibody-drug conjugates (ADCs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or mechanical properties.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and nonlinear optical materials.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-Cyclohexene-1-Carbonyl Chloride, 4-Methyl-, trans- (9Ci)
CAS No.	111055-03-9
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	trans-4-Methyl-2-cyclohexene-1-carbonyl chloride; (1R,4S)-4-Methyl-2-cyclohexene-1-carbonyl chloride; 4-Methyl-δ²-cyclohexene-1-carbonyl chloride; 4-Methyl-2-cyclohexenecarboxylic acid chloride; 4-Methyl-1,2,3,6-tetrahydrobenzoyl chloride; 4-Methyl-2-cyclohexenoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Cyclohexene-1-Carbonyl Chloride, 4-Methyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed and allowed to reach ambient temperature before opening to prevent condensation and hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.