Description

1-[(4-Fluorophenyl)Methyl]-3-Azetidinol is a versatile azetidine derivative, a key nitrogen-containing heterocyclic building block prized for its structural motif in advanced synthesis. This compound matters for its role as a crucial intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of the pharmacologically significant 3-hydroxyazetidine scaffold. Pharmaceutical and agrochemical research organizations need it to synthesize new drug candidates and crop protection agents, particularly those targeting neurological and metabolic pathways.

Application

• As a key chiral intermediate in the synthesis of pharmaceutical candidates, especially for central nervous system (CNS) and metabolic disease targets.
• Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• Building block for the development of agrochemicals, including herbicides and fungicides with novel modes of action.
• Precursor in the synthesis of ligands for catalysis and other specialty fine chemicals.
• Used in academic and industrial R&D for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	1-[(4-Fluorophenyl)Methyl]-3-Azetidinol
CAS No.	111043-49-3
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	3-Hydroxy-1-(4-fluorobenzyl)azetidine; 1-(4-Fluorobenzyl)azetidin-3-ol; 1-[(4-Fluorophenyl)methyl]azetidin-3-ol; 3-Azetidinol, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)-3-hydroxyazetidine; Azetidin-3-ol, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)-3-azetidinol
EINECS	Contact for details

Quality Control

Our 1-[(4-Fluorophenyl)Methyl]-3-Azetidinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.