Description

1-[(4-Isothiocyanatophenyl)Sulfonyl]-4-Methylpiperidine is a specialized sulfonyl isothiocyanate derivative, a high-value intermediate in advanced organic synthesis. Its unique bifunctional structure, featuring both a reactive isothiocyanate group and a sulfonyl-protected amine, makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical developers engaged in medicinal chemistry, chemical biology, and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, particularly those requiring sulfonamide or thiourea pharmacophores.
• Chemical Biology Probe Development: Used to create affinity-based probes for labeling and studying protein function, enzyme activity, and biomolecular interactions.
• Material Science Research: Serves as a cross-linking agent or monomer in the development of specialty polymers and advanced functional materials.
• Agrochemical Synthesis: Intermediate in the research and development of novel crop protection agents and herbicides.
• Bioconjugation: Facilitates the covalent attachment of molecules to proteins, antibodies, or other biomolecules for diagnostic and therapeutic applications.

Basic Information

Item	Details
Product Name	1-[(4-Isothiocyanatophenyl)Sulfonyl]-4-Methylpiperidine
CAS No.	111032-36-1
Molecular Formula	C13H16N2O2S2
Molecular Weight	296.41 g/mol
Synonyms	4-Methyl-1-[(4-isothiocyanatophenyl)sulfonyl]piperidine; 1-(4-Isothiocyanatobenzenesulfonyl)-4-methylpiperidine; 4-Methyl-1-(4-isothiocyanatophenylsulfonyl)piperidine; 4-Methylpiperidine-1-sulfonyl-4'-isothiocyanate benzene; p-Isothiocyanatobenzenesulfonyl-4-methylpiperidine; 111032-36-1; 4-Methyl-1-(4-isothiocyanatobenzene-1-sulfonyl)piperidine
EINECS	Contact for details

Quality Control

Every batch of 1-[(4-Isothiocyanatophenyl)Sulfonyl]-4-Methylpiperidine is manufactured under strict quality management protocols. We ensure compliance with relevant industry standards through rigorous in-process and final release testing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.