Description

1-[(4-Isothiocyanatophenyl)Sulfonyl]-3-Methylpiperidine is a specialized organic intermediate featuring a reactive isothiocyanate group and a sulfonyl linker. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the isothiocyanate moiety can be used for conjugation or as a pharmacophore.
• Bioconjugation Reagent: Used in biochemical research to modify proteins, peptides, or antibodies, leveraging the reactive isothiocyanate group to form stable thiourea bonds with amine groups.
• Agrochemical Synthesis: Serves as a building block for developing novel active ingredients in crop protection products, such as herbicides or fungicides.
• Material Science Research: Employed in the development of advanced polymers or functional materials where the incorporation of specific aromatic and heterocyclic structures is required.
• Chemical Probe Development: Utilized in medicinal chemistry to create tool compounds for target identification and validation in biological pathways.

Basic Information

Product Name	1-[(4-Isothiocyanatophenyl)Sulfonyl]-3-Methylpiperidine
CAS No.	111032-35-0
Molecular Formula	C13H16N2O2S2
Molecular Weight	296.41 g/mol
Synonyms	3-Methyl-1-[(4-isothiocyanatophenyl)sulfonyl]piperidine; 1-(4-Isothiocyanatobenzenesulfonyl)-3-methylpiperidine; 4-(3-Methylpiperidine-1-sulfonyl)phenyl isothiocyanate; 1-(4-Isothiocyanato-benzenesulfonyl)-3-methyl-piperidine; 3-Methyl-1-(4-isothiocyanatophenylsulfonyl)piperidine; 111032-35-0; 1-(4-Isothiocyanatophenylsulfonyl)-3-methylpiperidine
EINECS	Contact for details

Quality Control

Our 1-[(4-Isothiocyanatophenyl)Sulfonyl]-3-Methylpiperidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.