Description

2-Methyl-2'-Deoxyadenosine is a chemically modified nucleoside analog, specifically a methylated derivative of deoxyadenosine. This structural modification is crucial for research into nucleic acid chemistry, enzymatic processes, and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in nucleoside synthesis, antiviral studies, and molecular biology applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside-based antiviral or anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving DNA polymerases, methyltransferases, and other nucleic acid-modifying enzymes.
• Antiviral Agent Development: Investigated for its potential activity against viral pathogens by incorporating into viral DNA/RNA to inhibit replication.
• Molecular Probe Synthesis: Acts as a precursor for labeled nucleosides (e.g., fluorescent or radioactive tags) used in diagnostic assays and imaging.
• Academic & Industrial R&D: Fundamental research tool in organic chemistry and medicinal chemistry for studying structure-activity relationships (SAR).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2-Methyl-2'-Deoxyadenosine
CAS No.	110952-90-4
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	2-Methyl-2'-deoxyadenosine; 2-Methyladenosine 2'-deoxy-; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-2-methyladenine; 2-Methyl-9-(2-deoxy-β-D-ribofuranosyl)adenine; 2-Me-dA; 2-Methyl-dA; 2-Methyl-deoxyadenosine; 2-Methyl-2'-deoxyadenosine (CAS 110952-90-4)
EINECS	Contact for details

Quality Control

Our 2-Methyl-2'-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with detailed results for traceability and compliance. Specifications are designed to meet the stringent requirements of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the product should be handled in a dry environment and the container kept sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.