Description

6-Amino-1-Arabinofuranosyl-1H-Pyrrolo(3,2-C)Pyridin-4(5H)-One is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer drugs, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of experimental compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor in the design of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleotide metabolism pathways.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry Development: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	6-Amino-1-Arabinofuranosyl-1H-Pyrrolo(3,2-C)Pyridin-4(5H)-One
CAS No.	110914-71-1
Molecular Formula	C12H15N3O5
Molecular Weight	281.26 g/mol
Synonyms	6-Amino-1-β-D-arabinofuranosyl-1H-pyrrolo[3,2-c]pyridin-4(5H)-one; 6-Amino-1-(β-D-arabinofuranosyl)-1,5-dihydro-4H-pyrrolo[3,2-c]pyridin-4-one; 6-Amino-1-(β-D-arabinofuranosyl)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridin-4-one; 1-(β-D-Arabinofuranosyl)-6-amino-1,5-dihydro-4H-pyrrolo[3,2-c]pyridin-4-one; Ara-TPDA; Nucleoside Analog Intermediate
EINECS	Contact for details

Quality Control

Our 6-Amino-1-Arabinofuranosyl-1H-Pyrrolo(3,2-C)Pyridin-4(5H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.