Description

2-[2-Hydroxyethyl]-9-[β-D-Ribofuranosyl]Hypoxanthine is a modified nucleoside derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a crucial building block and reference standard in the synthesis and study of novel nucleotide analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, enzymology studies, and the development of nucleotide-based therapeutics. The high-purity material is essential for ensuring the accuracy and reproducibility of experimental results in these critical fields.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving nucleoside kinases and polymerases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Life Science Reagents: Component in specialized kits and reagents for molecular biology and diagnostic assay development.

Basic Information

Product Name	2-[2-Hydroxyethyl]-9-[β-D-Ribofuranosyl]Hypoxanthine
CAS No.	110851-59-7
Molecular Formula	C12H16N4O6
Molecular Weight	312.28 g/mol
Synonyms	9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(2-hydroxyethyl)-6,9-dihydro-1H-purin-6-one; 2-(2-Hydroxyethyl)inosine analog; HE-Ribosylhypoxanthine; N2-(2-Hydroxyethyl)guanosine derivative (related); Modified Inosine Nucleoside; 9-β-D-Ribofuranosyl-2-(2-hydroxyethyl)hypoxanthine
EINECS	Contact for details

Quality Control

Our 2-[2-Hydroxyethyl]-9-[β-D-Ribofuranosyl]Hypoxanthine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and spectroscopic methods for structural verification, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.