Description

2-Vinyl-9-[β-D-Ribofuranosyl]Hypoxanthine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial synthetic intermediate and building block for the creation of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of modified nucleic acids and nucleoside-based therapeutics. The product is supplied with a focus on high purity and consistency to meet the stringent demands of modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Investigated as a precursor for chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid processing.
• Prodrug Development: Utilized in creating masked nucleoside derivatives designed for improved bioavailability and targeted delivery.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized nucleoside derivatives for research and clinical trials.

Basic Information

Product Name	2-Vinyl-9-[β-D-Ribofuranosyl]Hypoxanthine
CAS No.	110851-56-4
Molecular Formula	C₁₂H₁₄N₄O₅
Molecular Weight	294.26 g/mol
Synonyms	2-Vinylinosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-ethenyl-1,9-dihydro-6H-purin-6-one; 2-Vinyl-9-β-D-ribofuranosylhypoxanthine; 2-Vinyl-9-(β-D-ribofuranosyl)hypoxanthine; 2-Ethenyl-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; 2-Vinyl-9-ribofuranosylhypoxanthine
EINECS	Contact for details

Quality Control

Our 2-Vinyl-9-[β-D-Ribofuranosyl]Hypoxanthine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.