Description

n-(All-trans-Retinoyl)-DL-Leucine is a chemically modified derivative of retinoic acid, designed for enhanced stability and targeted delivery in advanced research and development. This compound is critical for scientists and formulators seeking to leverage the biological activity of retinoids with improved molecular properties. It is primarily utilized in the pharmaceutical and high-end cosmetic industries for the development of novel therapeutic agents and advanced skincare solutions.

Application

• Pharmaceutical R&D as a prodrug or synthetic intermediate for novel retinoid-based therapies targeting dermatological and oncological conditions.
• Cosmetic Science for the formulation of high-potency, stabilized anti-aging and skin-rejuvenating serums and creams.
• Biochemical Research as a tool compound to study retinoid metabolism, cellular signaling pathways, and receptor interactions.
• Nutraceutical Development for exploring advanced delivery systems of vitamin A derivatives in supplement formats.
• Reference Standard in analytical laboratories for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	n-(All-trans-Retinoyl)-DL-Leucine
CAS No.	110683-02-8
Molecular Formula	C26H37NO4
Molecular Weight	427.58 g/mol
Synonyms	N-Retinoyl-DL-leucine; Retinoyl leucine; All-trans-N-retinoyl-DL-leucine; Vitamin A acid leucine amide; DL-Leucine, N-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoyl]-; Leucine retinamide
EINECS	Contact for details

Quality Control

Our n-(All-trans-Retinoyl)-DL-Leucine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or GMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
All-trans Isomer Content	≥ 95.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.