Description

6-Azidohexanoic Acid Methyl Ester is a versatile bifunctional organic compound featuring both an azide group and a methyl ester. This molecular architecture makes it a valuable click chemistry reagent and a key building block for the synthesis of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for applications requiring precise molecular assembly.

Application

• Click Chemistry Reagent: Serves as a critical component in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for introducing functional handles or modifying pharmacokinetic properties.
• Bioconjugation Linker: Enables the site-specific labeling of proteins, antibodies, and other biomolecules with dyes, drugs, or solid supports.
• Polymer & Materials Science: Acts as a monomer or cross-linking agent for creating functionalized polymers, hydrogels, and smart materials with tailored properties.
• Chemical Probe Synthesis: Employed in the development of activity-based probes and diagnostic agents for biological research and assay development.
• Peptide & Protein Modification: Facilitates the post-translational modification or cyclization of peptides to enhance stability or biological activity.

Basic Information

Product Name	6-Azidohexanoic Acid Methyl Ester
CAS No.	110544-77-9
Molecular Formula	C7H13N3O2
Molecular Weight	171.20 g/mol
Synonyms	Methyl 6-azidohexanoate; 6-Azidohexanoic Acid Methyl Ester; Methyl 6-azidocaproate; Azidohexanoic Acid Methyl Ester; Hexanoic acid, 6-azido-, methyl ester; Methyl 5-azidopentanoate (common misnomer); 6-Azido Caproic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 6-Azidohexanoic Acid Methyl Ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to the presence of the azide functional group, avoid contact with strong acids and heavy metal salts.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.