Description

3',5'-Di-o-(4-Chlorobenzoyl)-5-(2-Dibromovinyl)-2'-Deoxyuridine is a specialized nucleoside analog derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and DNA replication pathways. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation therapeutic compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of experimental nucleoside-based antiviral drugs.
• Antiviral Research: Used in biochemical studies to investigate mechanisms of action against DNA viruses, such as herpesviruses and poxviruses.
• Oncology Research: Serves as a precursor for developing potential chemotherapeutic agents that inhibit tumor cell proliferation.
• Biochemical Probe: Utilized in enzymatic studies to understand substrate specificity and inhibition of viral thymidine kinases and DNA polymerases.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	3',5'-Di-o-(4-Chlorobenzoyl)-5-(2-Dibromovinyl)-2'-Deoxyuridine
CAS No.	110326-07-3
Molecular Formula	C26H20Br2Cl2N2O7
Molecular Weight	696.16 g/mol
Synonyms	5-(2-Dibromovinyl)-2'-deoxyuridine 3',5'-bis(4-chlorobenzoate); 3',5'-Di-O-(4-chlorobenzoyl)-5-(2-dibromovinyl)-2'-deoxyuridine; 2'-Deoxy-5-(2-dibromovinyl)uridine 3',5'-bis(4-chlorobenzoate); BVDU 3',5'-Di-(4-chlorobenzoate); (E)-5-(2,2-Dibromovinyl)-2'-deoxyuridine 3',5'-di-p-chlorobenzoate; Nucleoside Analog Intermediate; Antiviral Nucleoside Derivative
EINECS	Contact for details

Quality Control

Our 3',5'-Di-o-(4-Chlorobenzoyl)-5-(2-Dibromovinyl)-2'-Deoxyuridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.