Description

2',3'-Secouridine 4-Nitrophenyl 5'-Phosphate is a specialized nucleotide derivative and a key synthetic intermediate in advanced biochemical research and pharmaceutical development. This compound is valued for its role as a building block in the synthesis of modified oligonucleotides and nucleotide analogs, enabling critical studies in molecular biology and drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on antiviral and anticancer therapeutic development, as well as in the production of high-purity diagnostic reagents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, polymerases, and phosphodiesterases.
• Oligonucleotide Synthesis: Serves as a protected monomer or a specialized phosphoramidite building block for constructing modified DNA/RNA sequences.
• Proteomics & Diagnostics: Employed in the development of enzyme-linked assays and diagnostic kits for detecting specific enzymatic activities.
• Chemical Biology Probes: Used to create labeled or activatable probes for studying cellular processes and signal transduction pathways.
• Academic Research: A valuable tool for investigating nucleotide metabolism, enzyme mechanisms, and nucleic acid chemistry.

Basic Information

Product Name	2',3'-Secouridine 4-Nitrophenyl 5'-Phosphate
CAS No.	110238-02-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2',3'-Secouridine 4-nitrophenyl 5'-phosphate; 4-Nitrophenyl 2',3'-secouridine 5'-phosphate; 2',3'-Seco-uridine 4-nitrophenyl 5'-phosphate; Uridine, 2',3'-seco-, 5'-(4-nitrophenyl phosphate); 5'-O-(4-Nitrophenylphosphoryl)-2',3'-secouridine; 2',3'-SecoUridine 4-NPP 5'-Phosphate; Nucleotide analog intermediate; Modified nucleoside phosphate ester.
EINECS	Contact for details

Quality Control

Our 2',3'-Secouridine 4-Nitrophenyl 5'-Phosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and MS for structural confirmation, and stringent controls for moisture and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., argon or nitrogen) in a desiccator to maintain stability and prevent decomposition. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Individual impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.