Description

(5β,7α,12α)-7,12-Dihydroxy-3-Oxo-Cholestan-26-Oic Acid Methyl Ester CAS NO 110107-08-9 is a high-purity, synthetic steroidal intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block in the synthesis of complex bioactive molecules, particularly those targeting metabolic and endocrine pathways. It is primarily needed by pharmaceutical manufacturers and advanced research institutions engaged in the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bile acid analogs and steroidal drugs.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for exploring new therapeutic agents.
• Biochemical Studies: Employed in metabolic pathway research and enzyme inhibition studies related to cholesterol and bile acid metabolism.
• Process Chemistry: Serves as a high-value intermediate in the scalable production of target Active Pharmaceutical Ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for studying steroid chemistry and structure-activity relationships.

Basic Information

Product Name	(5β,7α,12α)-7,12-Dihydroxy-3-Oxo-Cholestan-26-Oic Acid Methyl Ester
CAS No.	110107-08-9
Molecular Formula	C₂₈H₄₆O₆
Molecular Weight	478.66 g/mol
Synonyms	Methyl 3-Oxo-7α,12α-dihydroxy-5β-cholan-24-oate; 7α,12α-Dihydroxy-3-oxo-5β-cholan-24-oic Acid Methyl Ester; 3-Oxo-7α,12α-dihydroxy-5β-cholanoic Acid Methyl Ester; Methyl 7α,12α-dihydroxy-3-oxo-5β-cholan-24-oate; CAS 110107-08-9; 5β-Cholan-24-oic Acid, 7α,12α-dihydroxy-3-oxo-, Methyl Ester, (5β,7α,12α)-
EINECS	Contact for details

Quality Control

Our (5β,7α,12α)-7,12-Dihydroxy-3-Oxo-Cholestan-26-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.