Description

9-Bromo-16α,17-Epoxy-11β-Hydroxyprogesterone is a high-purity, synthetic steroid derivative with a bromine substitution and an epoxy functional group, serving as a critical advanced intermediate in pharmaceutical synthesis. This compound is valued for its precise molecular structure, which enables the targeted synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized steroid hormones and related therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid and progestin analogs for therapeutic applications.
• Steroid Research: Used in academic and industrial R&D to study structure-activity relationships (SAR) and develop new steroid-based drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for the commercial manufacturing of steroid APIs.
• Biochemical Tool: Utilized in biochemical assays to investigate steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	9-Bromo-16α,17-Epoxy-11β-Hydroxyprogesterone
CAS No.	110053-24-2
Molecular Formula	C21H27BrO4
Molecular Weight	423.34 g/mol
Synonyms	9-Bromo-11β-hydroxy-16α,17α-epoxypregn-4-ene-3,20-dione; 9-Bromo-16α,17α-epoxy-11β-hydroxyprogesterone; 9-Bromo-11β,16α-epoxy-17α-hydroxyprogesterone (common name); 9-Br-11β-OH-16α,17α-epoxy-P4; Pregna-4-ene-3,20-dione, 9-bromo-11,16-epoxy-17-hydroxy-, (11β,16α,17α)-; 110053-24-2; 9-Bromo-11β-hydroxy-16α,17α-oxidopregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our 9-Bromo-16α,17-Epoxy-11β-Hydroxyprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.