Description

8,25-Dihydroxy-9,10-Seco-4,6,10(19)-Cholestatrien-3-One is a high-purity, synthetic secosteroid derivative, structurally related to vitamin D analogs. This compound is valued for its role as a critical pharmaceutical intermediate and a versatile research chemical in the development of novel therapeutic agents. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for advanced synthesis projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced vitamin D analogs and other steroidal pharmaceuticals.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and receptor binding assays.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs targeting nuclear hormone receptors.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for studying secosteroid chemistry and biology.

Basic Information

Product Name	8,25-Dihydroxy-9,10-Seco-4,6,10(19)-Cholestatrien-3-One
CAS No.	109947-25-3
Molecular Formula	C₂₇H₄₂O₃
Molecular Weight	414.62 g/mol
Synonyms	8,25-Dihydroxy-9,10-secocholesta-4,6,10(19)-trien-3-one; 9,10-Secocholesta-4,6,10(19)-trien-3-one, 8,25-dihydroxy-; Vitamin D3 derivative intermediate; Secosteroid trienone; 8α,25-Dihydroxyprovitamin D3; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3β,25-diol-8-one derivative
EINECS	Contact for details

Quality Control

Our 8,25-Dihydroxy-9,10-Seco-4,6,10(19)-Cholestatrien-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.