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2-(Acetylamino)-2-Deoxy-4,6-o-(Phenylmethylene)-α-D-Glucopyranose 1-[Bis(Phenylmethyl) Phosphate] CAS NO 109304-69-0


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CAS No.:109304-69-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(Acetylamino)-2-Deoxy-4,6-o-(Phenylmethylene)-α-D-Glucopyranose 1-[Bis(Phenylmethyl) Phosphate] is a sophisticated, protected carbohydrate derivative that serves as a critical intermediate in advanced organic synthesis. This compound matters for its role in constructing complex glycoconjugates and nucleoside analogs, where precise control over stereochemistry and functional group protection is paramount. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including antiviral agents and targeted drug delivery systems.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside-based antiviral and anticancer drug candidates.
  • Glycochemistry Research: Used in the study and synthesis of complex oligosaccharides and glycopeptides for biological activity screening.
  • Prodrug Development: Serves as a protected phosphate ester precursor for creating membrane-permeable prodrugs of bioactive nucleotides.
  • Chemical Biology Tool: Employed in the preparation of labeled or modified sugar nucleotides for enzymatic studies and metabolic pathway analysis.
  • Process Chemistry: Utilized in scale-up routes for the GMP production of specialty carbohydrate-active pharmaceutical ingredients (APIs).

Basic Information

Product Name 2-(Acetylamino)-2-Deoxy-4,6-o-(Phenylmethylene)-α-D-Glucopyranose 1-[Bis(Phenylmethyl) Phosphate]
CAS No. 109304-69-0
Molecular Formula C29H32NO9P
Molecular Weight 569.54 g/mol
Synonyms 1-Dibenzyl 2-Acetamido-2-deoxy-4,6-O-benzylidene-α-D-glucopyranosyl Phosphate; N-Acetyl-4,6-O-benzylidene-α-D-glucosamine 1-Dibenzyl Phosphate; GlcNAc(benzylidene)-α-D-1-dibenzyl phosphate; Benzylidene-protected N-acetylglucosamine dibenzyl phosphate; 2-Acetamido-2-deoxy-4,6-O-benzylidene-α-D-glucopyranose 1-(dibenzyl phosphate); 109304-69-0; α-D-Glucopyranose, 2-(acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-, 1-[bis(phenylmethyl) phosphate]
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Quality Control

Our 2-(Acetylamino)-2-Deoxy-4,6-o-(Phenylmethylene)-α-D-Glucopyranose 1-[Bis(Phenylmethyl) Phosphate] is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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