Description

2'-Deoxy-2'-Fluoro-6-S-Methyl-6-Thio-Arabino-Inosine is a high-purity, modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. Its unique fluorinated and thio-modified arabino-inosine structure makes it an essential intermediate for medicinal chemists and researchers in biotechnology and pharmaceutical companies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation antiviral and anticancer nucleotide analogs.
• Antiviral Drug Research: Used in the development of novel therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigated as a building block for prodrugs and targeted cancer therapies that interfere with DNA/RNA synthesis.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to probe nucleic acid metabolism and related pathways.
• Pre-clinical Development: Utilized in the formulation and testing of experimental drug candidates in pre-clinical models.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro-6-S-Methyl-6-Thio-Arabino-Inosine
CAS No.	109304-12-3
Molecular Formula	C11H13FN4O4S
Molecular Weight	316.31 g/mol
Synonyms	6-Methylthio-2'-deoxy-2'-fluoroinosine; 2'-Deoxy-2'-fluoro-6-methylthio-9H-purin-9-yl-β-D-arabinofuranoside; 2'-F-6-S-Me-ara-Inosine; 2'-Fluoro-6-methylthio-9-(β-D-arabinofuranosyl)purine; 6-(Methylthio)-2'-deoxy-2'-fluoroinosine; 2'-Fluoro-6-methylmercaptopurine arabinoside; 6-Methylsulfanyl-2'-deoxy-2'-fluoroinosine; 2'-F-ara-6-S-Me-Ino
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro-6-S-Methyl-6-Thio-Arabino-Inosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization and purity verification. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.