Description

3,7,12-Trihydroxy-5-Cholenoic Acid is a key bile acid derivative and an important intermediate in the synthesis of various steroidal compounds. This compound matters for its role as a critical building block in pharmaceutical research and development, particularly for creating therapeutic agents targeting liver and metabolic functions. It is primarily needed by manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for producing high-value active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Biochemical Research: Used as a reference standard and reagent in studies of cholesterol metabolism, liver function, and bile acid pathways.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the production of complex steroidal molecules.
• API Development: Employed in the research and development of new active pharmaceutical ingredients targeting cholestatic liver diseases.
• Diagnostic Reagents: Can be utilized in the formulation of calibrators and controls for clinical diagnostic assays.

Basic Information

Product Name	3,7,12-Trihydroxy-5-Cholenoic Acid
CAS No.	108906-88-3
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-chol-24-enoic Acid; 5β-Chol-24-enoic-3α,7α,12α-triol; 3,7,12-Trihydroxycholenic Acid; 3α,7α,12α-Trihydroxy-5β-cholen-24-oic Acid; 5β-Cholen-24-oic-3α,7α,12α-triol; Cholenic Acid, 3,7,12-trihydroxy-; 5β-Cholenoic Acid-3α,7α,12α-triol
EINECS	Contact for details

Quality Control

Our 3,7,12-Trihydroxy-5-Cholenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.